Archaeological digs in Africa revealed alien artifacts that humans
were genetically engineered by a advanced alien race (space jockeys). These "Alien Gods" also terraformed Earth in order to make it habitable for human. Amongst finds at the digs were coordinates found in artifacts that showed the route to the Alien God's home-world.
Following finding the coordinates, months later Weyland Corporation launched the spaceship
USCSS Prometheus and it's crew into deep space to speak with them. Due to faster than light travel only a few years later USCSS Prometheus entered the Zeta 2 Riticuli star system and LV223. There they found Alien Temples aligned in rows, inside they found what they were searching for, a living Space Jockey.
By Weyland's wish the surviving crew set off for the Derelict and Space Jockey. They find that the Space Jockey is hostile, killing them and leaving only one surviving crew member who must escape and notify the crew aboard Prometheus.